Supplements & nutrition

L-Arginine and L-Citrulline for Blood Pressure:...

Two amino acids, one nitric oxide pathway, and decades of clinical data. We review the mechanisms, trials, and meta-analyses behind arginine and citrulline supplementation for blood pressure — including dosing,...

L-Arginine and L-Citrulline for Blood Pressure:...

Two amino acids, one nitric oxide pathway, and decades of clinical data. We review the mechanisms, trials, and meta-analyses behind arginine and citrulline supplementation for blood pressure — including dosing,...

Navy and burgundy gradient icon representing the hypertension supplements blog

Supplements for Those with Hypertension

Over 1.28 billion people live with hypertension. Clinical research across 22+ randomised trials shows L-arginine and L-citrulline can reduce systolic blood pressure by 6–10 mmHg through a well-understood nitric oxide...

Supplements for Those with Hypertension

Over 1.28 billion people live with hypertension. Clinical research across 22+ randomised trials shows L-arginine and L-citrulline can reduce systolic blood pressure by 6–10 mmHg through a well-understood nitric oxide...

2D molecular structures of L-Arginine and L-Citrulline

L-Arginine + L-Citrulline for Exercise Performa...

We reviewed 22 studies on L-arginine and L-citrulline for exercise performance. The evidence supports modest benefits for muscular endurance and recovery, but effects are small and most pronounced in less-trained...

L-Arginine + L-Citrulline for Exercise Performa...

We reviewed 22 studies on L-arginine and L-citrulline for exercise performance. The evidence supports modest benefits for muscular endurance and recovery, but effects are small and most pronounced in less-trained...

Using L-Arginine to improve VO2 max and overall...

Boost Your Athletic Performance with L-Arginine Since initially investigating the use of L-Arginine in sports performance I have been eager to personally test the supplementation within my own regime. When...

Using L-Arginine to improve VO2 max and overall...

Boost Your Athletic Performance with L-Arginine Since initially investigating the use of L-Arginine in sports performance I have been eager to personally test the supplementation within my own regime. When...

L-arginine and L-citrulline molecular structures

The NO Paradox: Why Citrulline Beats Arginine a...

Oral arginine has ~20% bioavailability. Citrulline bypasses the liver entirely. Here is the pharmacokinetics of why citrulline raises NO more effectively — and why combining them makes sense.

The NO Paradox: Why Citrulline Beats Arginine a...

Oral arginine has ~20% bioavailability. Citrulline bypasses the liver entirely. Here is the pharmacokinetics of why citrulline raises NO more effectively — and why combining them makes sense.

L-arginine and L-citrulline molecular structures

Arginine & Citrulline: It's Not Your Heart Rate...

Arginine and citrulline don't lower your heart rate — they reduce the workload on your heart. Evidence from 3 RCTs in heart failure patients shows how the NO pathway changes...

Arginine & Citrulline: It's Not Your Heart Rate...

Arginine and citrulline don't lower your heart rate — they reduce the workload on your heart. Evidence from 3 RCTs in heart failure patients shows how the NO pathway changes...

L-arginine and L-citrulline molecular structures

Arginine & Citrulline: Lower Blood Pressure, Be...

Clinical research across 22 RCTs shows L-arginine supplementation reduces systolic blood pressure by 6 mmHg. Combined with citrulline, reductions reach 10 mmHg. Here is what the evidence means for athletes.

Arginine & Citrulline: Lower Blood Pressure, Be...

Clinical research across 22 RCTs shows L-arginine supplementation reduces systolic blood pressure by 6 mmHg. Combined with citrulline, reductions reach 10 mmHg. Here is what the evidence means for athletes.

L-arginine and L-citrulline molecular structures

The Vascular Pipeline: How Arginine and Citrull...

Learn how arginine and citrulline support vascular compliance, vasodilation, and muscle blood flow during exercise — what the clinical research actually shows.

The Vascular Pipeline: How Arginine and Citrull...

Learn how arginine and citrulline support vascular compliance, vasodilation, and muscle blood flow during exercise — what the clinical research actually shows.